Geron: Able To Face The Pageant With Imetelstat In Decrease-Chance MDS (GERN)

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Geron Company (NASDAQ:GERN) is creating imetelstat for decrease threat myelodysplastic syndromes (LR-MDS) and myelofibrosis (MF). Whilst GERN introduced good fortune in its section 3 IMerge find out about in LR-MDS in January 2023, the MF indication is not as with regards to approval with an

Geron Corporation pipeline imetelstat gern

Determine 1: GERN pipeline. Notice that the IMerge find out about has already produced a good readout. (GERN site.)

imetelstat IMerge results geron

Determine 2: Screenshot of the desk of effects from GERN’s IMerge find out about of Imetelstat in LR MDS. (GERN press unlock, January 4, 2023.)

Reblozyl for very low to intermediate risk MDS

Determine 3: Screenshot of Prescribing Knowledge for luspatercept, word the LR MDS indication. The beta thalassemia indication is not related to this dialogue. (Reblozyl Prescribing Knowledge from Reblozyl site.)

NEJM Medalist results luspatercept reblozyl

Determine 4: Share of sufferers reaching transfusion independence within the section 3 Medalist find out about of luspatercept (Reblozyl) in MDS. (N Engl J Med 2020; 382:140-151. )

LR MDS treatment paradigm landscape reblozyl luspatercept imetelstat

Determine 5: GERN evaluate of the LR MDS remedy panorama. Notice the lifestyles of information from trials of luspatercept as a first-line agent might alternate the remedy panorama. (GERN Company Presentation, Might 2023.)

GERN imetelstat LR MDS market evolution

Determine 6: Effects from marketplace analysis in 50 US hematologists. (GERN Company Presentation, Might 2023.)

GERN geron corporation loan payments

Determine: Screenshot of bills to be made underneath the present phrases of GERN’s mortgage settlement. (GERN 10-Q, filed Might 2023.)

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